Product Name	SP-B/Surfactant Protein B
Chinese Name	肺表面活性蛋白B抗体
Alias	18 kDa pulmonary surfactant protein; 18 kDa pulmonary-surfactant protein; 6 kDa protein; Pulmonary surfactant apoprotein PSP B; Pulmonary surfactant associated protein B 18kD; Pulmonary surfactant associated protein B; Pulmonary surfactant associated proteolipid SPL Phe; SFTB3; SFTP3; SFTPB; SFTPB surfactant; Surfactant pulmonary associated protein B; Prosurfactant Protein B; pulmonary surfactant-associated glycoprotein B; proSP B; PSP B; PSPB; PSPB_MOUSE; Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteolipid SPL(Phe); SFTB3; SFTP3; SFTPB; SP B; SPB.
literatures	Specific References (1) | SL1034R has been referenced in 1 publications. [IF=1.19] Kanie et al. Suppressive effects of the expectorant drug ambroxol hydrochloride on quartz-induced lung inflammation in F344 rats. (2017) J.Toxicol.Pathol. 30:153-159 IHC-P ; Rat. PubMed:28458453
Research Area	Tumour Cardiovascular Signal transduction The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,Mouse,Rat
Applications	WB=1:500-2000 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	41kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse SP-B: 291-377/377
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Human,Mouse,Rat1M TBS(pH7.4) with 1% BSA, Human,Mouse,Rat3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.Homodimer; disulfide-linked. Secreted, extracellular space. Function: Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted, extracellular space, surface film. Similarity: Contains 1 saposin A-type domain. Contains 3 saposin B-type domains. SWISS: P07988 Gene ID: 6439 Database links: Entrez Gene: 6439 Human Entrez Gene: 20388 Mouse Omim: 178640 Human SwissProt: P15781 Cow SwissProt: P07988 Human SwissProt: P50405 Mouse Unigene: 512690 Human Unigene: 46033 Mouse 肺泡表面活性物质B（SP-B）也属糖Binding protein家族,参与肺泡表面活性膜的形成和代谢,除在Ⅱ型细胞中强烈表达外，在细支气管、支气管上皮内也有灶性表达。SP-B是疏水性蛋白，主要效应是促进磷脂吸附和分布到肺泡气-液交界面，促进磷脂单分子层的形成，只有这种单分子层磷脂才能使表面张力降低到最低水平。

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