Product Name	Carboxypeptidase H
Chinese Name	胰羧肽酶E抗体
Alias	Carboxypeptidase E; Carboxypeptidase-E; Carboxypeptidase H; Carboxypeptidase H precursor; CarboxypeptidaseE; CarboxypeptidaseH; CBPE_HUMAN; CPE; Cph 1; CPH; Cph1; Enkephalin convertase; Entephalin convertase; Prohormone processing carboxypeptidase; Prohormone-processing carboxypeptidase.
Research Area	Tumour Cell biology immunology Neurobiology Growth factors and hormones Diabetes Endocrinopathy
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat(predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit)
Applications	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	48kDa
Cellular localization	The nucleus cytoplasmic The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Carboxypeptidase E: 201-300/476
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin. Subcellular Location: Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions. soform 2: Nucleus. Tissue Specificity: Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas. Similarity: Belongs to the peptidase M14 family. SWISS: P16870 Gene ID: 1363 Database links: Entrez Gene: 1363 Human Entrez Gene: 12876 Mouse Entrez Gene: 25669 Rat Omim: 114855 Human SwissProt: P04836 Cow SwissProt: P16870 Human SwissProt: Q00493 Mouse SwissProt: P15087 Rat Unigene: 75360 Human Unigene: 31395 Mouse Unigene: 470333 Mouse Unigene: 7149 Rat
Product Picture	Sample: Cerebrum (Rat) Lysate at 40 ug Primary: Anti- Carboxypeptidase H (SL6478R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 48 kD