Product Name	Recombinant Rabbit Anti-CFL1 Monoclonal Antibody
Cat No.	SLA0767M
Alias	CFL; HEL-S-15; cofilin; Cof; COF1_HUMAN; CFL1; 18 kDa phosphoprotein (p18); Cofilin, non-muscle isoform; COF1_MOUSE; COF1_RAT; cofilin 1; cofilin 1 (non-muscle)
Host Species	Mouse
Clonality	Monoclonal
Clone No.	2G3
React Species	Human,Mouse,Rat
Applications	WB (1:1000-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Synthesized peptide derived from human Cofilin
Purification	Affinity-chromatography using specific immunogen.
Concentration	1mg/ml
Predicted MW.	20 kDa
Swiss-Prot	P23528
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	cofilin 1 (CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM , Apr 2004]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.