Product Name	Recombinant Rabbit Anti-VDR Monoclonal Antibody
Cat No.	SLA0758M
Alias	NR1I1; PPP1R163; VDR_HUMAN; VDR; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1; VDR_MOUSE; VDR_RAT; vitamin D receptor; vitamin D (1,25- dihydroxyvitamin D3) receptor; protein phosphatase 1, regulatory subunit 163; 1,25- dihydroxyvitamin D3 receptor
Host Species	Mouse
Isotype	IgG1/Kappa
Clonality	Monoclonal
Clone No.	5D9
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Synthesized peptide derived from human Vitamin D Receptor
Purification	affinity purified by Protein G
Concentration	1mg/ml
Predicted MW.	47 kDa
Swiss-Prot	P11473
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	vitamin D (1 ,25- dihydroxyvitamin D3) receptor (VDR) Homo sapiens This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways , such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq , Feb 2011]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.