Product Name	Recombinant Rabbit Anti-KRT6A Monoclonal Antibody
Cat No.	SLA0746M
Alias	K6E; KRT6E; PPKNEFD; CK-6C; CK-6E; CK6A; CK6C; CK6D; K6A; K6C; K6D; KRT6C; KRT6D; PC3; CK-6B; CK6B; K6B; KRTL1; PC2; PC4; 2310016L08Rik; CK-6A; K6[a]; Krt2-6a; Krt2-6c; MK6a; mK6[a]; Krt2-6b; mK6[b]; K2C6A_HUMAN; KRT6A; Cytokeratin-6A (CK-6A); Cytokeratin-6D (CK-6D); Keratin-6A (K6A); Type-II keratin Kb6; K2C6B_HUMAN; KRT6B; Cytokeratin-6B (CK-6B); Keratin-6B (K6B); Type-II keratin Kb10; K2C6C_HUMAN; Cytokeratin-6C (CK-6C); Cytokeratin-6E (CK-6E); Keratin K6h; Keratin-6C (K6C); Type-II keratin Kb12; K2C6A_MOUSE; Keratin-6-alpha (mK6-alpha); Ker2; Krt2-6; Krt6; K2C6B_MOUSE; Keratin-6-beta (mK6-beta); K6-beta; keratin 6A; keratin 6C; keratin 6D; keratin 6A, type II
Host Species	Mouse
Isotype	IgG2a/Kappa
Clonality	Monoclonal
Clone No.	5G11
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Synthesized peptide derived from human Cytokeratin 6
Purification	affinity purified by Protein G
Concentration	1mg/ml
Predicted MW.	60 kDa
Swiss-Prot	P02538
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue , the stratified epithelial lining of oral mucosa and esophagus , the outer root sheath of hair follicles , and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition , peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathoge
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.