Product Name	Recombinant Rabbit Anti-PRF1 Monoclonal Antibody
Cat No.	SLA0453M
Chinese Name	穿孔素单克隆抗体
Alias	HPLH2; P1; PFP; Pfn; Prf-1; Cyta; RATCYTA; PERF_HUMAN; PRF1; Cytolysin; Lymphocyte pore-forming protein (PFP); PERF_MOUSE; Lymphocyte pore-forming protein; PERF_RAT; perforin 1; perforin 1 (pore forming protein); Perforin; perforin 1 (preforming protein);
Host Species	Mouse
Clonality	Monoclonal
Clone No.	3C3
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human Perforin
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	59 kDa
Subcellular Location	Cytoplasm
Gene ID	5551
Swiss-Prot	P14222
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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