Product Name	Recombinant Rabbit Anti-EIF2AK3 Monoclonal Antibody
Cat No.	SLA3553M
Alias	PEK; PERK; WRS; E2AK3_HUMAN; EIF2AK3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase (HsPEK); Protein tyrosine kinase EIF2AK3; 2.7.11.1; E2AK3_MOUSE; Pancreatic eIF2-alpha kinase; E2AK3_RAT; eukaryotic translation initiation factor 2 alpha kinase 3; pancreatic eIF-2alpha kinase; PKR-like ER kinase; Eukaryotic translation initiation factor 2-alpha kinase 3 (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK); Eukaryotic translation initiation factor 2-alpha kinase 3; HsPEK
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	8A6
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	9451
Swiss-Prot	Q9NZJ5
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.