Product Name	Recombinant Rabbit Anti-ZC3H12A Monoclonal Antibody
Cat No.	SLA3443M
Alias	MCPIP; MCPIP-1; MCPIP1; Reg1; dJ423B22.1; ZC12A_BOVIN; ZC3H12A; Zinc finger CCCH domain-containing protein 12A; 3.1.-.-; ZC12A_HUMAN; Monocyte chemotactic protein-induced protein 1 (MCP-induced protein 1 | MCPIP-1); Regnase-1 (Reg1); ZC12A_MOUSE; zinc finger CCCH-type containing 12A; MCP induced protein 1; Ribonuclease ZC3H12A (MCP-induced protein 1) (Zinc finger CCCH domain-containing protein 12A)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	11A3
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	80149
Swiss-Prot	Q5D1E8
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.