Product Name	Recombinant Rabbit Anti-XPC Monoclonal Antibody
Cat No.	SLA3373M
Alias	RAD4; XP3; XPCC; p125; XPC_HUMAN; XPC; Xeroderma pigmentosum group C-complementing protein; XPC_MOUSE; Xeroderma pigmentosum group C-complementing protein homolog; XPC complex subunit, DNA damage recognition and repair factor; xeroderma pigmentosum, complementation group C; xeroderma pigmentosum group C protein
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	4H0
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	7508
Swiss-Prot	Q01831
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.