Product Name	Recombinant Rabbit Anti-XIAP Monoclonal Antibody
Cat No.	SLA3364M
Alias	API3; BIRC4; IAP-3; ILP1; MIHA; XLP2; hIAP-3; hIAP3; XIAP_HUMAN; XIAP; Baculoviral IAP repeat-containing protein 4; IAP-like protein (ILP | hILP); Inhibitor of apoptosis protein 3 (IAP-3 | hIAP-3 | hIAP3); RING-type E3 ubiquitin transferase XIAP; X-linked inhibitor of apoptosis protein (X-linked IAP); 2.3.2.27; IAP3; X-linked inhibitor of apoptosis; baculoviral IAP repeat-containing 4; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase; IAP-like protein 1; E3 ubiquitin-protein ligase XIAP; IAP-like protein; ILP; hILP; Inhibitor of apoptosis protein 3; X-linked inhibitor of apoptosis protein; X-linked I
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	2G4
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	331
Swiss-Prot	P98170
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.