Product Name	Recombinant Rabbit Anti-DUSP3 Monoclonal Antibody
Cat No.	SLA3330M
Alias	VHR; 2210015O03Rik; 5031436O03Rik; T-DSP11; RGD1560049; DUS3_HUMAN; DUSP3; Dual specificity protein phosphatase VHR; Vaccinia H1-related phosphatase (VHR); 3.1.3.16; 3.1.3.48; DUS3_MOUSE; dual specificity phosphatase 3; vaccinia virus phosphatase VH1-related; Dual specificity protein phosphatase 3; Vaccinia H1-related phosphatase
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	6B7
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	1845
Swiss-Prot	P51452
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast ca
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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