Product Name	Recombinant Rabbit Anti-MAP2K4 Monoclonal Antibody
Cat No.	SLA3315M
Alias	JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SAPKK-1; SAPKK1; SEK1; SERK1; SKK1; MAPKK 4; MP2K4_HUMAN; MAP2K4; MAP kinase kinase 4; JNK-activating kinase 1; MAPK/ERK kinase 4 (MEK 4); SAPK/ERK kinase 1 (SEK1); Stress-activated protein kinase kinase 1 (SAPK kinase 1 | SAPKK-1 | SAPKK1); c-Jun N-terminal kinase kinase 1 (JNKK); 2.7.12.2; MP2K4_MOUSE; C-JUN N-terminal kinase kinase 1 (JNK kinase 1 | JNKK 1); mitogen-activated protein kinase kinase 4; SAPK/ERK kinase 1; stress-activated protein kinase kinase 1; c-Jun NH2-terminal kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 4; MAPK/ERK kinase 4; MEK 4; SAPK kinase 1; c-Jun N-terminal kinase kinase 1
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3B1
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	6416
Swiss-Prot	P45985
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.