Product Name	Recombinant Rabbit Anti-CTNNB1 Monoclonal Antibody
Cat No.	SLA3288M
Alias	CTNNB; EVR7; MRD19; NEDSDV; armadillo; Bfc; Catnb; Mesc; CTNB1_HUMAN; CTNNB1; Beta-catenin; CTNB1_MOUSE; CTNB1_RAT; catenin beta 1; catenin (cadherin-associated protein), beta 1 (88kD); catenin (cadherin-associated protein), beta 1, 88kDa; catenin (cadherin-associated protein), beta 1; Catenin-β; b-catenin; Beta catenin; Cadherin associated protein; Catenin (cadherin associated protein), beta 1, 88 kDa; Catenin beta-1; CHBCAT; DKFZp686D02253; FLJ25606; FLJ37923; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289; OK/SW-cl.35
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	6C4
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	1499
Swiss-Prot	P35222
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.