Product Name	Recombinant Rabbit Anti-FURIN Monoclonal Antibody
Cat No.	SLA3215M
Alias	FUR; PACE; PCSK3; SPC1; 9130404I01Rik; FURIN_HUMAN; FURIN; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme (PACE); 3.4.21.75; FURIN_MOUSE; Prohormone convertase 3; FURIN_RAT; furin, paired basic amino acid cleaving enzyme; paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein); furin (paired basic amino acid cleaving enzyme); proprotein convertase subtilisin/kexin 3; subtilisin-like proprotein convertase 1; Furin (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	4G4
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	5045
Swiss-Prot	P09958
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix m
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.