Product Name	Recombinant Rabbit Anti-CRYAA Monoclonal Antibody
Cat No.	SLA3193M
Alias	CRYA1; CTRCT9; HSPB4; Acry-1; Crya-1; DAcry-1; lop18; CRYAA_BOVIN; CRYAA; CRYAA_LOXAF; CRYAA_CAVPO; CRYAA_MESAU; CRYAA_HORSE; CRYAA_HUMAN; Heat shock protein beta-4 (HspB4); Heat shock protein family B member 4; CRYAA_MOUSE; CRYAA_PIG; CRYAA_RABIT; CRYAA_RAT; CRYAA_MACMU; crystallin alpha A; crystallin, alpha A; Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5D7
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	1409
Swiss-Prot	P02489
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.