Product Name	Recombinant Rabbit Anti-GJB6 Monoclonal Antibody
Cat No.	SLA3183M
Alias	CX30; DFNA3; DFNA3B; DFNB1B; ECTD2; ED2; EDH; HED; HED2; Cxnf; D14Bwg0506e; CXB6_HUMAN; GJB6; Connexin-30 (Cx30); CXB6_MOUSE; Cxn-30; gap junction protein beta 6; ectodermal dysplasia 2, hidrotic (Clouston syndrome); gap junction protein, beta 6 (connexin 30); gap junction protein, beta 6; gap junction protein, beta 6, 30kDa; connexin 30; Gap junction beta-6 protein; Connexin-30
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3G4
React Species	Human,Mouse
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	10804
Swiss-Prot	O95452
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.