Product Name	Recombinant Rabbit Anti-ZWINT Monoclonal Antibody
Cat No.	SLA3180M
Alias	ZWINT_HUMAN; ZWINT; ZW10 interactor; ZW10-interacting protein 1 (Zwint-1); HZwint-1; KNTC2AP; SIP30; ZWINT1; ZW10 interacting kinetochore protein; SNAP25 interacting protein of 30 kDa; ZW10 interactor (ZW10-interacting protein 1) (Zwint-1)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	10D1
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) Flow-Cyt (1:50-100) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	11130
Swiss-Prot	O95229
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	ZWINT is a component of the MIS12 complex, which is required for kinetochore function and spindle checkpoint activity. ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase. ZWINT is detectable on the kinetochore till late anaphase. Inhibition of ZWINT expression results in chromosome missegregation, spindle checkpoint failure and, ultimately, cell death upon cytokinesis.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.