Product Name	Recombinant Rabbit Anti-TLR5 Monoclonal Antibody
Cat No.	SLA3167M
Alias	MELIOS; SLE1; SLEB1; TIL3; TLR5_HUMAN; TLR5; Toll/interleukin-1 receptor-like protein 3; TLR5_MOUSE; toll like receptor 5; systemic lupus erythematosus susceptibility 1; toll-like receptor 5; Toll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	8G2
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	7100
Swiss-Prot	O60602
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.