Product Name	Recombinant Rabbit Anti-SOCS1 Monoclonal Antibody
Cat No.	SLA3155M
Alias	AISIMD; CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP-3; TIP3; Cish7; SOCS1_HUMAN; SOCS1; JAK-binding protein (JAB); STAT-induced STAT inhibitor 1 (SSI-1); Tec-interacting protein 3 (TIP-3); SOCS1_MOUSE; SOCS1_RAT; suppressor of cytokine signaling 1; JAK-binding protein; STAT-induced STAT inhibitor 1; Tec-interacting protein 3
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	6C3
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	8651
Swiss-Prot	O15524
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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