Product Name	Recombinant Rabbit Anti-PEDV Monoclonal Antibody
Cat No.	SLA0633M
Chinese Name	猪流行性腹泻单克隆抗体
Alias	SPIKE_PEDV7; Spike glycoprotein; S glycoprotein; E2; Peplomer protein;
Host Species	Mouse
Isotype	IgG2a
Clonality	Monoclonal
Clone No.	2G5
Applications	ELISA () Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant PEDV Spike glycoprotein S1:26-734/1383
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	151 kDa
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The porcine epidemic diarrhea virus (PEDV) is a member of the coronavirus family, causing deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant morbidity and mortality, poses a huge threat to the swine industry. The currently developed vaccines and drugs are only effective against the classic GI strains that were prevalent before 2010, while there is no effective control against the GII variant strains that are currently a global pandemic. In this review, we summarize the latest progress in the biology of PEDV, including its transmission and origin, structure and function, evolution, and virus–host interaction, in an attempt to find the potential virulence factors influencing PEDV pathogenesis. We conclude with the mechanism by which PEDV components antagonize the immune responses of the virus, and the role of host factors in virus infection. Essentially, this review serves as a valuable reference for the development of attenuated virus vaccines and the potential of host factors as antiviral targets for the prevention and control of PEDV infection.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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