Product Name	Recombinant Rabbit Anti-JEV Monoclonal Antibody
Cat No.	SLA0629M
Chinese Name	猪乙脑病毒包膜蛋白单克隆抗体
Alias	Q90105_9FLAV; E protein/ envelope protein;
Host Species	Mouse
Isotype	IgG2a
Clonality	Monoclonal
Clone No.	8C4
Applications	ELISA () Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant JEV Envelope protein E
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	131 kDa
Swiss-Prot	Q90105
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Involved in immune evasion, pathogenesis and viral replication. Once cleaved off the polyprotein, is targeted to three destinations: the viral replication cycle, the plasma membrane and the extracellular compartment. Essential for viral replication. Required for formation of the replication complex and recruitment of other non-structural proteins to the ER-derived membrane structures. Excreted as a hexameric lipoparticle that plays a role against host immune response. Antagonizing the complement function. Binds to the host macrophages and dendritic cells. Inhibits signal transduction originating from Toll-like receptor 3 (TLR3).
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.