Product Name	Recombinant Rabbit Anti-BTK (p-Y551) Monoclonal Antibody
Cat No.	SLA2963M
Chinese Name	磷酸化酪氨酸蛋白激酶BTK重组兔单抗
Alias	AGMX1; AT; ATK; BPK; IGHD3; IMD1; PSCTK1; XLA; xid; BTK_HUMAN; BTK; Agammaglobulinemia tyrosine kinase (ATK); B-cell progenitor kinase (BPK); Bruton tyrosine kinase; 2.7.10.2; BTK_MOUSE; Kinase EMB; Bruton agammaglobulinemia tyrosine kinase; Bruton's tyrosine kinase; BTK (phospho-Y551); p-BTK; phospho-BTK; BTK (phospho-Tyr551)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5C12
React Species	Human
Applications	WB (1:1000-2000) ICC/IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human BTK around the phosphorylation site of Y551
Purification	affinity purified by Protein A
Predicted MW.	76 kDa
Observed MW.	74 kDa
Gene ID	695
Swiss-Prot	Q06187
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling.Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation.After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.