Product Name	Recombinant Rabbit Anti-MAP2K5 Monoclonal Antibody
Cat No.	SLA2879M
Chinese Name	丝裂原活化蛋白激酶激酶5重组兔单抗
Alias	HsT17454; MAPKK5; MEK5; PRKMK5; MP2K5_HUMAN; MAP2K5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5 (MEK 5); 2.7.12.2; MKK5; MP2K5_MOUSE; MP2K5_RAT; mitogen-activated protein kinase kinase 5; dual specificity mitogen-activated protein kinase kinase 5; MAPK/ERK kinase 5
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
React Species	Human
Applications	WB (1:1000-2000) ICC/IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human MEK5
Purification	affinity purified by Protein A
Predicted MW.	50 kDa
Observed MW.	48 kDa
Gene ID	5607
Swiss-Prot	Q13163
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via promotion of STUB1/CHIP-mediated ubiquitination and degradation of ICER-type isoforms of CREM.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.