Product Name	Recombinant Rabbit Anti-HBEGF Monoclonal Antibody
Cat No.	SLA2026M
Chinese Name	肝素结合性表皮生长因子重组兔单抗
Alias	DTR; DTS; DTSF; HEGFL; HBEGF_HUMAN; HBEGF; heparin binding EGF like growth factor; diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); heparin-binding EGF-like growth factor; Diphtheria toxin receptor (heparin-binding EGF-like growth factor); heparin-binding epidermal growth factor
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
React Species	Human,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human HB EGF
Purification	affinity purified by Protein A
Predicted MW.	23 kDa
Observed MW.	23 kDa
Gene ID	1839
Swiss-Prot	Q99075
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.