Product Name	Recombinant Rabbit Anti-RNF8 Monoclonal Antibody
Cat No.	SLA1701M
Chinese Name	环指蛋白8重组兔单抗
Alias	hRNF8; RNF8_HUMAN; RNF8; RING finger protein 8; RING-type E3 ubiquitin transferase RNF8; 2.3.2.27; KIAA0646
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
React Species	Human,Rat
Applications	WB (1:1000-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human RNF8
Purification	affinity purified by Protein A
Predicted MW.	56 kDa
Observed MW.	63 kDa
Gene ID	9025
Swiss-Prot	O76064
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.