Product Name	Recombinant Rabbit Anti-ROCK2 Monoclonal Antibody
Cat No.	SLA1624M
Chinese Name	Rho相关蛋白激酶2重组兔单抗
Alias	ROCK-II; B230113H15Rik; ROKalpha; Rho-kinase; Rock2m; mKIAA0619; ROK; ROCK2_HUMAN; ROCK2; Rho kinase 2; Rho-associated, coiled-coil-containing protein kinase 2; Rho-associated, coiled-coil-containing protein kinase II (ROCK-II); p164 ROCK-2; 2.7.11.1; KIAA0619; ROCK2_MOUSE; Rho associated coiled-coil containing protein kinase 2
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
React Species	Human,Mouse,Rat
Applications	ICC/IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human ROCK2
Purification	affinity purified by Protein A
Predicted MW.	161 kDa
Observed MW.	161 kDa
Subcellular Location	Cytoplasm
Gene ID	9475
Swiss-Prot	O75116
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.