Product Name	CCL19 | ELC/MIP3B Recombinant Rabbit mAb
Cat No.	SLM-61386R
Chinese Name	巨噬细胞炎性蛋白19重组兔单抗
Alias	CKb11; ELC; MIP-3b; MIP3B; SCYA19; Gm2023; exodus-3; CCL19_HUMAN; CCL19; Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine (EBI1 ligand chemokine | ELC); Macrophage inflammatory protein 3 beta (MIP-3-beta); Small-inducible cytokine A19; CCL19_MOUSE; C-C motif chemokine ligand 19; small inducible cytokine subfamily A (Cys-Cys), member 19; chemokine (C-C motif) ligand 19; CC chemokine ligand 19; macrophage inflammatory protein 3-beta; beta chemokine exodus-3; EBI1-ligand chemokine
Host Species	Rabbit
Isotype	IgG
Clonality	Recombinant
React Species	Human
Applications	Flow-Cyt (1:50-100) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human CCL19
Purification	affinity purified by Protein A
Predicted MW.	11 kDa
Observed MW.	11 kDa
Subcellular Location	Extracellular
Gene ID	6363
Swiss-Prot	Q99731
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.