Product Name	Recombinant Rabbit Anti-IRAK3 Monoclonal Antibody
Cat No.	SLA1368M
Chinese Name	白细胞介素1受体相关蛋白激酶M重组兔单抗
Alias	ASRT5; IRAKM; 4833428C18Rik; IRAK-M; IRAK3_HUMAN; IRAK3; IRAK-3; IL-1 receptor-associated kinase M (IRAK-M); Inactive IL-1 receptor-associated kinase 3; IRAK3_MOUSE; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
React Species	Human
Applications	WB (1:1000-2000) IP (1:20-50) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human IRAK3
Purification	affinity purified by Protein A
Predicted MW.	68 kDa
Observed MW.	68 kDa
Gene ID	11213
Swiss-Prot	Q9Y616
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors.Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.