Product Name	Recombinant Rabbit Anti-MET Monoclonal Antibody
Cat No.	SLA0483M
Chinese Name	肝细胞生长因子受体单克隆抗体
Alias	AUTS9; DA11; DFNB97; HGFR; RCCP2; c-Met; HGF; Par4; MET_HUMAN; MET; HGF receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor (SF receptor); Tyrosine-protein kinase Met; 2.7.10.1; MET_MOUSE; MET_RAT; MET proto-oncogene, receptor tyrosine kinase; met proto-oncogene; hepatocyte growth factor receptor
Host Species	Mouse
Isotype	IgG
Clonality	Monoclonal
Clone No.	10F1
React Species	Human,Mouse,Rat
Applications	WB (1:500-1000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human MET
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	156 kDa
Subcellular Location	Membrane
Gene ID	4233
Swiss-Prot	P08581
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.