Product Name	Recombinant Rabbit Anti-STAT1 (p-Y701) Monoclonal Antibody
Cat No.	SLA2991M
Chinese Name	磷酸化信号转导与转录激活因子1重组兔单抗
Alias	CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91; 2010005J02Rik; DD6G4-4; STAT1_HUMAN; STAT1; Transcription factor ISGF-3 components p91/p84; STAT1_MOUSE; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; STAT1 (phospho-Y701); p-STAT1; phospho-STAT1; STAT1 (phospho-Tyr701)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	4F11
React Species	Human
Applications	WB (1:1000-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human STAT1 around the phosphorylation site of Y701
Purification	affinity purified by Protein A
Predicted MW.	87 kDa
Observed MW.	87 kDa
Gene ID	6772
Swiss-Prot	P42224
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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