Product Name	Rabbit Anti-DACT2 Polyclonal Antibody
Cat No.	SLA0010
Chinese Name	Dapper2蛋白抗体
Alias	C6orf116; DAPPER2; DPR2; bA503C24.7; 2900084M21Rik; A630024E20; Frd2; DACT2_HUMAN; DACT2; Dapper antagonist of catenin 2; DACT2_MOUSE; mDpr2; dishevelled binding antagonist of beta catenin 2; chromosome 6 open reading frame 116; dapper homolog 2, antagonist of beta-catenin (xenopus); dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ICC/IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human Dact2
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	83 kDa
Gene ID	168002
Swiss-Prot	Q5SW24
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Dapper2 is a 774 amino acid protein that exists as multiple alternatively spliced isoforms and is a mammalian homolog of the Xenopus laevis protein dapper. Containing a C-terminal PDZ-binding motif, Dapper2 is thought to promote the lysosomal degradation of nodal receptors, possibly functioning to negatively regulate the nodal signaling pathway. The gene encoding Dapper2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.