Product Name	Recombinant Rabbit Anti-PLCG1 Monoclonal Antibody
Cat No.	SLA1038M
Chinese Name	磷酸化磷酯酶Cγ1重组兔单抗
Alias	IDAA; NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1; Cded; Plc-1; Plc-gamma1; Plcg-1; PPLCA; PLCG1_HUMAN; PLCG1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II (PLC-II); Phospholipase C-gamma-1 (PLC-gamma-1); 3.1.4.11; PLCG1_MOUSE; PLCG1_RAT; phospholipase C gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C, gamma 1; PLCG1 (phospho-Y783); p-PLCG1; phospho-PLCG1; PLCG1 (phospho-Tyr783)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3G7
React Species	Human
Applications	WB (1:500-2000) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated Synthesised phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr783
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	148 kDa
Observed MW.	155 kDa
Subcellular Location	Nucleus
Gene ID	5335
Swiss-Prot	P19174
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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