Product Name	Recombinant Rabbit Anti-NLRP3 Monoclonal Antibody
Cat No.	SLA1017M
Chinese Name	细胞凋亡诱导蛋白NALP3重组兔单抗
Alias	AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1; AII/AVP; Mmig1; NLRP3_HUMAN; NLRP3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1 (CLR1.1); Cold-induced autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1; 3.6.4.-; NLRP3_MOUSE; Cold autoinflammatory syndrome 1 protein homolog; Mast cell maturation-associated-inducible protein 1; NLR family pyrin domain containing 3; cold autoinflammatory syndrome 1; deafness, autosomal dominant 34; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3G12
React Species	Human
Applications	WB (1:500-2000) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human NALP3
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	118 kDa
Observed MW.	118 kDa
Subcellular Location	Cytoplasm
Gene ID	114548
Swiss-Prot	Q96P20
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.