Product Name	Recombinant Rabbit Anti-PRKAA2 Monoclonal Antibody
Cat No.	SLA1155M
Chinese Name	腺苷单磷酸活化蛋白激酶α2重组小鼠单抗
Alias	AMPK; AMPK2; AMPKa2; PRKAA; 2310008I11Rik; A830082D05; AMPKalpha2; AAPK2_HUMAN; PRKAA2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase (ACACA kinase); Hydroxymethylglutaryl-CoA reductase kinase (HMGCR kinase); 2.7.11.1; AAPK2_MOUSE; AAPK2_RAT; protein kinase AMP-activated catalytic subunit alpha 2; protein kinase, AMP-activated, alpha 2 catalytic subunit
Host Species	Mouse
Isotype	IgG2b,k
Clonality	Monoclonal
Clone No.	5D8
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human AMPK alpha 2
Concentration	1mg/ml
Predicted MW.	62 kDa
Observed MW.	62 kDa
Subcellular Location	Nucleus
Gene ID	5563
Swiss-Prot	P54646
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.