Product Name	Recombinant Rabbit Anti-GCLM Monoclonal Antibody
Cat No.	SLA3099M
Chinese Name	γ 谷氨酰半胱氨酸连接酶调节亚基重组兔单抗
Alias	GLCLR; Gcmc; GSH0_HUMAN; GCLM; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier subunit; GSH0_MOUSE; GSH0_RAT; glutamate-cysteine ligase modifier subunit; glutamate-cysteine ligase, modifier subunit; gamma-glutamylcysteine synthetase
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	8F7
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human GCLM
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	31 kDa
Observed MW.	30 kDa
Subcellular Location	Cytoplasm
Gene ID	2730
Swiss-Prot	P48507
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.