Product Name	Recombinant Rabbit Anti-LAT (p-Y220) Monoclonal Antibody
Cat No.	SLA2920M
Chinese Name	磷酸化T细胞活化连接蛋白重组兔单抗
Alias	IMD52; LAT1; pp36; p36-38; LAT_HUMAN; LAT; 36 kDa phosphotyrosine adapter protein (pp36); LAT_MOUSE; LAT_RAT; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; LAT (phospho-Y220); p-LAT; phospho-LAT; LAT (phospho-Tyr220)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	2D10
React Species	Human,Rat
Applications	WB (1:500-2000) IP (1:20-50) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human LAT around the phosphorylation site of Y220
Purification	affinity purified by Protein A
Predicted MW.	28 kDa
Observed MW.	36-38 kDa
Subcellular Location	Membrane
Gene ID	27040
Swiss-Prot	O43561
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.