Product Name	Recombinant Rabbit Anti-NOLC1 Monoclonal Antibody
Cat No.	SLA2638M
Chinese Name	丙型肝炎病毒NS5A反式蛋白13重组兔单抗
Alias	NOPP130; NOPP140; NS5ATP13; P130; Srp40; NOLC1_HUMAN; NOLC1; 140 kDa nucleolar phosphoprotein (Nopp140); Hepatitis C virus NS5A-transactivated protein 13 (HCV NS5A-transactivated protein 13); Nucleolar 130 kDa protein; Nucleolar phosphoprotein p130; KIAA0035; NOLC1_RAT; nucleolar and coiled-body phosphoprotein 1
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
React Species	Human
Applications	WB (1:1000-2000) ICC/IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human NOLC1
Purification	affinity purified by Protein A
Predicted MW.	74 kDa
Observed MW.	110 kDa
Subcellular Location	Nucleus
Gene ID	9221
Swiss-Prot	Q14978
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification.Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.