Product Name	Recombinant Rabbit Anti-UFD1 Monoclonal Antibody
Cat No.	SLA2608M
Chinese Name	泛素融合降解样蛋白1重组兔单抗
Alias	UFD1L; UFD1_HUMAN; UFD1; Ubiquitin fusion degradation protein 1 (UB fusion protein 1); UFD1_MOUSE; Ubiquitin fusion degradation protein 1 homolog (UB fusion protein 1); UFD1_RAT; ubiquitin recognition factor in ER associated degradation 1; ubiquitin fusion degradation 1-like; ubiquitin fusion degradation 1 like (yeast)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	1C5
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) Flow-Cyt (1:50-100) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human UFD1
Purification	affinity purified by Protein A
Predicted MW.	35 kDa
Observed MW.	40 kDa
Gene ID	7353
Swiss-Prot	Q92890
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.