Product Name	Recombinant Rabbit Anti-SBDS Monoclonal Antibody
Cat No.	SLA2398M
Chinese Name	SBDS蛋白重组兔单抗
Alias	CGI-97; SDO1; SDS; SWDS; 4733401P19Rik; SBDS_BOVIN; SBDS; Shwachman-Bodian-Diamond syndrome protein homolog; SBDS_HUMAN; Shwachman-Bodian-Diamond syndrome protein; SBDS_MOUSE; Protein 22A3; SBDS_RAT; SBDS ribosome maturation factor; Shwachman-Bodian-Diamond syndrome; SBDS, ribosome assembly guanine nucleotide exchange factor
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	6H3
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human SBDS
Purification	affinity purified by Protein A
Predicted MW.	29 kDa
Observed MW.	30 kDa
Gene ID	51119
Swiss-Prot	Q9Y3A5
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.