Product Name	Recombinant Rabbit Anti-CASP5 Monoclonal Antibody
Cat No.	SLA2364M
Chinese Name	半胱胺酸蛋白酶蛋白5重组兔单抗
Alias	ICE(rel)III; ICEREL-III; ICH-3; CASP5_HUMAN; CASP5; CASP-5; ICE(rel)-III; Protease ICH-3; Protease TY; 3.4.22.58; ICH3; caspase 5; caspase 5, apoptosis-related cysteine protease; caspase 5, apoptosis-related cysteine peptidase
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	11H6
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human Caspase 5
Purification	affinity purified by Protein A
Predicted MW.	50 kDa
Observed MW.	48 kDa
Subcellular Location	Cytoplasm
Gene ID	838
Swiss-Prot	P51878
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Thiol protease that acts as a mediator of programmed cell death.Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD): cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.