Product Name	Recombinant Rabbit Anti-DOCK2 Monoclonal Antibody
Cat No.	SLA2273M
Chinese Name	细胞质分裂付出蛋白2重组兔单抗
Alias	IMD40; CED-5; Hch; MBC; AABR07029272.1; DOCK2_HUMAN; DOCK2; KIAA0209; DOCK2_MOUSE; Protein Hch; dedicator of cytokinesis 2; dedicator of cyto-kinesis 2
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	10F1
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human Dedicator of cytokinesis protein 2
Purification	affinity purified by Protein A
Predicted MW.	212 kDa
Observed MW.	200 kDa
Subcellular Location	Membrane
Gene ID	1794
Swiss-Prot	Q92608
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.