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Product Name Recombinant Rabbit Anti-VPS18 Monoclonal Antibody Cat No. SLA2112M Chinese Name 液泡蛋白分选蛋白18重组兔单抗 Alias PEP3; 9930024E13Rik; VPS18_HUMAN; VPS18; hVPS18; KIAA1475; VPS18_MOUSE; VPS18 core subunit of CORVET and HOPS complexes; vacuolar protein sorting protein 18; vacuolar protein sorting 18 homolog (S. cerevisiae); VPS18, CORVET/HOPS core subunit Host Species Rabbit Isotype IgG Clonality Monoclonal Clone No. 2A10 React Species Human,Mouse,Rat Applications WB (1:1000-2000)
Flow-Cyt (1:50-100)
ICC/IF (1:50-200)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Immunogen A synthesized peptide derived from human VPS18 Purification affinity purified by Protein A Predicted MW. 110 kDa Observed MW. 100 kDa Gene ID 57617 Swiss-Prot Q9P253 Storage 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.Background Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.
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