Product Name	Recombinant Rabbit Anti-MMP17 Monoclonal Antibody
Cat No.	SLA1862M
Chinese Name	基质金属蛋白酶-17重组兔单抗
Alias	MMP-17; MT4-MMP; MT4MMP; MTMMP4; MMP17_HUMAN; MMP17; Membrane-type matrix metalloproteinase 4 (MT-MMP 4 | MTMMP4); Membrane-type-4 matrix metalloproteinase (MT4-MMP | MT4MMP); 3.4.24.-; MMP17_MOUSE; matrix metallopeptidase 17; matrix metalloproteinase 17 (membrane-inserted); matrix metallopeptidase 17 (membrane-inserted)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3C11
React Species	Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human MMP17
Purification	affinity purified by Protein A
Predicted MW.	67 kDa
Observed MW.	58 kDa
Subcellular Location	Membrane
Gene ID	4326
Swiss-Prot	Q9ULZ9
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.