Product Name	Recombinant Rabbit Anti-SMURF2 Monoclonal Antibody
Cat No.	SLA1856M
Chinese Name	Smad蛋白E3泛素连接酶2重组兔单抗
Alias	2810411E22Rik; RGD1310067; Q52LL1_HUMAN; SMUF2_HUMAN; SMURF2; hSMURF2; HECT-type E3 ubiquitin transferase SMURF2; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2; 2.3.2.26; SMUF2_MOUSE; Q3TT87_MOUSE; Q5IRE6_MOUSE; SMAD specific E3 ubiquitin protein ligase 2
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5D1
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human SMURF2
Purification	affinity purified by Protein A
Predicted MW.	86 kDa
Observed MW.	77 kDa
Gene ID	64750
Swiss-Prot	Q52LL1
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent degradation, thereby down-regulating TGF-beta signaling.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.