Product Name	Recombinant Rabbit Anti-MELK Monoclonal Antibody
Cat No.	SLA1741M
Chinese Name	蛋白激酶MPK38重组兔单抗
Alias	HPK38; MPK38; mKIAA0175; MELK_HUMAN; MELK; hMELK; Protein kinase Eg3 (pEg3 kinase); Protein kinase PK38 (hPK38); Tyrosine-protein kinase MELK; 2.7.11.1; KIAA0175; MELK_MOUSE; Protein kinase PK38 (mPK38); Pk38; maternal embryonic leucine zipper kinase
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	7A9
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human MELK
Purification	affinity purified by Protein A
Predicted MW.	75 kDa
Observed MW.	75 kDa
Gene ID	9833
Swiss-Prot	Q14680
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1. Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.