Product Name	Recombinant Rabbit Anti-TYR Monoclonal Antibody
Cat No.	SLA1527M
Chinese Name	酪氨酸酶重组兔单抗
Alias	ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3; TYRO_HUMAN; TYR; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB; 1.14.18.1; tyrosinase; oculocutaneous albinism IA
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	20C5
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human Tyrosinase
Purification	affinity purified by Protein A
Predicted MW.	60 kDa
Observed MW.	75 kDa
Subcellular Location	Cytoplasm
Gene ID	7299
Swiss-Prot	P14679
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.