Product Name	ARRB1 | beta-Arrestin-1 (p-S412) Recombinant Rabbit mAb
Cat No.	SLM-61196R
Chinese Name	磷酸化β-抑制蛋白1重组兔单抗
Alias	ARB1; ARR1; 1200006I17Rik; G430100A01Rik; BARRES; ARRB1_HUMAN; ARRB1; Arrestin beta-1; Non-visual arrestin-2; ARRB1_MOUSE; ARRB1_RAT; arrestin beta 1; arrestin, beta 1; arrestin 2; ARRB1 | beta-Arrestin-1 (phospho-S412); p-beta-Arrestin-1; phospho-beta-Arrestin-1; p-ARRB1; ARRB1 | beta-Arrestin-1 (phospho-Ser412)
Host Species	Rabbit
Isotype	IgG
Clonality	Recombinant
Clone No.	8E9
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human beta Arrestin 1 around the phosphorylation site of S412
Purification	affinity purified by Protein A
Concentration
Predicted MW.	47 kDa
Observed MW.	50 kDa
Subcellular Location	N/A
Gene ID	408
Swiss-Prot	P49407
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.