Product Name	Recombinant Rabbit Anti-GABRB1 Monoclonal Antibody
Cat No.	SLA1164M
Chinese Name	γ1氨基丁酸受体GABAA Rβ1重组兔单抗
Alias	DEE45; EIEE45; B230208N19Rik; Gabrb-1; GARB1; GBRB1_HUMAN; GABRB1; GABA(A) receptor subunit beta-1 (GABAAR subunit beta-1); GBRB1_MOUSE; GBRB1_RAT; gamma-aminobutyric acid type A receptor subunit beta1; gamma-aminobutyric acid (GABA) A receptor, beta 1; GABA(A) receptor, beta 1
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5H8
React Species	Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human GABRB1
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	51 kDa
Observed MW.	48 kDa
Subcellular Location	Membrane
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (g-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R©1-3, GABAA R∂, GABAA R gamma, GABAA R delta 1 and GABAA R delta 2. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2 and -3). The GABA transporters function to terminate GABA action.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.