Product Name	Recombinant Rabbit Anti-ITGAM Monoclonal Antibody
Cat No.	SLA1117M
Chinese Name	整合素αM/巨噬细胞表面分子重组兔单克隆抗体
Alias	CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; ITAM_HUMAN; ITGAM; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; ITAM_MOUSE; integrin subunit alpha M; integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide); integrin, alpha M (complement component 3 receptor 3 subunit); human neutrophil antigen 4; complement component 3 receptor 3 subunit; macrophage-1 antigen alpha subunit
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	17A4
React Species	Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human CD11b
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	125 kDa
Observed MW.	180 kDa
Subcellular Location	Membrane
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.