Product Name	Recombinant Rabbit Anti-IGF2R Monoclonal Antibody
Cat No.	SLA1107M
Chinese Name	胰岛素样生长因子2受体重组兔单抗
Alias	CI-MPR; CIMPR; CD222; CI-M6PR; M6P-R; M6P/IGF2R; MPR 300; MPR1; MPR300; MPRI; IGF-IIR; Igfr2; MPRI_BOVIN; IGF2R; CI Man-6-P receptor; M6PR; 300 kDa mannose 6-phosphate receptor (MPR 300); Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor (IGF-II receptor); M6P; MPRI_HUMAN; M6P/IGF2 receptor (M6P/IGF2R); MPRI_MOUSE; insulin like growth factor 2 receptor; cation-independent mannose-6 phosphate receptor
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	10H16
React Species	Human
Applications	WB (1:500-1000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human IGF2R
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	300 kDa
Observed MW.	300 kDa
Subcellular Location	Cytoplasm
Gene ID	3482
Swiss-Prot	P11717
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.